Importance of VWF & Factor VIII

wilate is the only VWF/FVIII complex that was developed specifically for the treatment of VWD.1-3

wilate is formulated to provide a balanced, 1:1 ratio of VWF and FVIII, as patients with VWD may have varying levels of deficiency in VWF and/or FVIII 4

  • VWF and FVIII are both essential to maintaining hemostasis2
    • VWF is essential to primary hemostasis and FVIII stability
    • FVIII is an important accelerator of secondary hemostasis
  • wilate helps restore the balance of both factors
Importance of VWF and FVII
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A balanced ratio of VWF and FVIII may help optimize dosing.

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References
  1. wilate Full Prescribing Information. Hoboken, NJ: Octapharma; rev 2016.
  2. Kessler CM, et al. Thromb Haemost. 2011;106:279-288.
  3. Stadler M, et al. Biologicals. 2006;34:281-288.
  4. Berntorp E, et al. Haemophilia. 2009;15:122-130. 5. Data on file. Hoboken, NJ: Octapharma USA Inc; 2018.